By J. De Groote (auth.), P. Fondu MD, O. Thijs MD (eds.)

ISBN-10: 9400960069

ISBN-13: 9789400960060

ISBN-10: 9400960085

ISBN-13: 9789400960084

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Additional info for Haemostatic Failure in Liver Disease

Example text

9. 10. 11. 12. 13. 14. 15. Stenflo J. A new vitamin K-dependent protein. Chem 251: 355-63, 1976 Kisiel W. Human plasma protein C. Invest. L. T. Activation of protein C in vivo. Invest. T. Functional properties of an endothelial cell cofactor for thrombin-catalyzed activation of protein C. Biol. Chern. G. Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C. Sci. G. T. Isolation of a membrane bound cofactor for thrombin catalyzed activation of protein C. Biol.

But we were getting calibration curves with normal pooled rat plasma. 24 ORAL ANTICOAGULANTS: UNEXPECTED SIDE-EFFECTS OR NEW FIELDS 'OF APPLICATION? G. D. BERG, M. M. SOUTE, MENNO DE METZ AND CEES VERMEER* 1. SUMMARY Vitamin K-dependent carboxylase is found in liver and in a number of non-hepatic tissues vessel wall. partial such as: It is shown, inhibition of the testis, lung, kidney, spleen and that the dosages of warfarin, clotting factor synthesis arterial required for a also affects the non-hepatic vitamin K-dependent systems.

Giddings Yes, we did not have a reference material, we did not have a reference standards in rats; what we did, was to pool a lot of rat plasma and to use that to relate to humans. We were unhappy about calling it a quantitated value in the assay; simply we have just shorten the clotting time. But we were getting calibration curves with normal pooled rat plasma. 24 ORAL ANTICOAGULANTS: UNEXPECTED SIDE-EFFECTS OR NEW FIELDS 'OF APPLICATION? G. D. BERG, M. M. SOUTE, MENNO DE METZ AND CEES VERMEER* 1.

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Haemostatic Failure in Liver Disease by J. De Groote (auth.), P. Fondu MD, O. Thijs MD (eds.)


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